Carsten Burkhardt's Web Project Paeonia - The Peony Library

Paeonia-Literatur 2005

Cheng Fangyun 2005 Chinese Flare Mudan 166p. ISBN 7-5038-3968-6 book on Rockii-hybrid tree peonies in chinese language, with many pictures

Hong D Y & Castroviejo S, 2005:(1682) Proposal to conserve the name Paeonia broteri against P. lusitanica Mill. Taxon 54(1): 211-212. (link to a local copy .pdf-file)

Hong D Y & Pan K Y, 2005: Notes on taxonomy of Paeonia Sect. Moutan DC. Acta Phytotax. Sin. 43(2):169-177 (PDF: http://www.plantsystematics.com/qikan/public/tjdjl.asp?wenjianming=f04-0065.pdf&id=11110) (link to a local copy .pdf-file)

Hong D Y & Pan K Y, 2005: Additional notes on taxonomy of Paeonia sect. Moutan DC. Acta Phytotax. Sin. 43(3):284-287 (PDF: http://www.plantsystematics.com/qikan/public/tjdjl.asp?wenjianming=f04-0082.pdf&id=11134 ) (link to a local copy .pdf-file) [This paper deals with six combinations proposed in 2001 in Paeonia sect. Moutan. Paeonia linyanshanii (S. G. Haw & Lauener) B. A. Shen and P. linyanshanii ssp. taibaishanica (D. Y. Hong) B. A. Shen are recognized as illegitimate names, P. ostii T. Hong & J. X. Zhang ssp. lishizhenenii (lishizhenii) (B. A. Shen) B. A. Shen is reduced to synonymy of P. ostii, P. delavayi Franch. ssp. angustiloba (Rehder & E. H. Wilson) B. A. Shen and P. delavayi ssp. lutea (Delavay ex Franch.) B. A. Shen are reduced to synonymy of P. delavayi, and P. delavayi ssp. ludlowii (Stern & Taylor) B. A. Shen is reduced to synonymy of P. ludlowii (Stern & Taylor) D. Y. Hong.]

Hong D Y : Paeonia in the Mediterranean & Caucasus, Presentation on the International Peony Symposium in Munich. May 7 2005

Li Jiajue (Ed.) 2005, Zhongguo Mudan PinZhong Tuzhi [Xibei, Xinan, Jiangnan] Jingwen ban, (Chinese Tree Peony Cultivar Groups [Northwest, Southwest,

Southern Yangtse] (English Edition) China Forestry Publishing House, 2005. ISBN 7503840404,

siehe (link) content of the book see here.

Liu ZQ, Zhou H, Liu L, Jiang ZH, Wong YF, Xie Y, Cai X, Xu HX, Chan K. Influence of co-administrated sinomenine on pharmacokinetic fate of paeoniflorin in unrestrained conscious rats. J Ethnopharmacol. 2005 May 13;99(1):61-7. [Abstract: Paeonia lactiflora Pall. (Ranunculaceae) root and Sinomenium acutum Rehder and Wilson (Menispermaceae) stem are two herbs widely used in Chinese medicine to treat rheumatoid arthritis. While, in theory, either herb could be used alone, in practice, Chinese medicine practitioners prescribe them together. Studies on pharmacokinetic interaction between the active constituents of these two herbs (paeoniflorin and sinomenine, respectively) provide empirical evidence to support their clinical practice. A single dose of paeoniflorin (150 mg/kg) alone and with sinomenine hydrochloride (90 mg/kg) was administered by gastric gavage to unrestrained conscious male Sprague-Dawley rats (n=6, 250-300 g). Blood samples were collected periodically via a jugular vein before and after dosing from 10 min to 12 h. A high-performance liquid chromatographic (HPLC) assay was developed to determine the plasma concentrations of paeoniflorin. Non-compartmental pharmacokinetic profiles were constructed by using the software PK Solutions 2.0. The pharmacokinetic parameters were compared using unpaired Student t-test. After co-administration of sinomenine, the peak plasma concentration of paeoniflorin was elevated (P<0.01), the peak time was delayed (P<0.01), the AUC(0-t) was increased (P<0.001), the mean residence time (MRT) was prolonged (P<0.01), the C(L) was decreased (P<0.01) and the V(d) was reduced (P<0.05). These results indicate that sinomenine hydrochloride at 90 mg/kg significantly improved the bioavailability of paeoniflorin in rats.] School of Chinese Medicine, Hong Kong Baptist University, Kowloon Tong, Kowloon, Hong Kong, PR China.

Mi XJ, Chen SW, Wang WJ, Wang R, Zhang YJ, Li WJ, Li YL., Anxiolytic-like effect of paeonol in mice., Pharmacol Biochem Behav. 2005 Jun 19; [Department of Pharmacology, Shenyang Pharmaceutical University, Box 41, 103 Wenhua Road, 110016 Shenyang, P.R. China.] [Abstract: The present study in mice compared the putative anxiolytic-like effect of paeonol, a phenolic component from the root bark of Paeonia moutan, with the benzodiazepine diazepam in the elevated plus maze and the light/dark box-test. The comparison was also with regard to locomotor activity (open-field test) and myorelaxant potential (inclined plane test). As with 2 mg/kg diazepam, paeonol (at 17.5 mg/kg) increased the percentage of time spent on open arms in the elevated plus maze and increased the time spent in the light area of the light/dark box (at 8.75 and 17.5 mg/kg). Since paeonol, in contrast to diazepam, had no effect on either the number of squares entered in the open-field test or in the inclined plane test, its side-effect profile is considered as superior to the benzodiazepine.] PMID: 15970315 [PubMed - as supplied by publisher]

Page, Martin, The gardener's peony: herbaceous and tree peonies, 2005, Timber Press 267p. ISBN 0-88192-694-9

Rho S, Chung HS, Kang M, Lee E, Cho C, Kim H, Park S, Kim HY, Hong M, Shin M, Bae H. Inhibition of production of reactive oxygen species and gene expression profile by treatment of ethanol extract of moutan cortex radicis in oxidative stressed PC12 cells. Biol Pharm Bull. 2005 Apr;28(4):661-6. [Abstract: Moutan Cortex Radicis (MCR) is one of the most widely used Oriental medicines. In this study, we assessed the reducing effect of ethanol extract of MCR on hydrogen peroxide-induced reactive oxygen production, the main cause of cell damage or death in PC12 cells. The viability of cells treated with 1 mg/ml of MCR was significantly restored from that of oxidative-stressed PC12 cells. Measurement of intracellular reactive oxygen species (ROS) generation was determined using the H(2)DCFDA assay. MCR at 1-0.01 mg/ml concentration inhibited ROS production in oxidative-stressed cells. To identify candidate genes responsible for the anti-oxidative effects of MCR on PC12 cells, an oligonucleotide microarray analysis was performed. The result of gene expression profiles showed that 10 genes were up-regulated and 7 were down-regulated in MCR plus hydrogen peroxide treated cells compared with hydrogen peroxide treated cells. Among them, heme oxygenase (HO) and cathechol-O-methyltransferase (COMT) are related to regulation of ROS generation and the others are known to regulate cell survival and progression. Subsequently, we performed real-time RT-PCR to quantify the ROS related gene. MCR treatment increased the expression of HO by 370% and COMT by 280% at the concentration of 1 mg/ml. These findings suggest that MCR inhibits the production of ROS and cytotoxicity by oxidative-stressed PC12 cells through over-expression of HO and COMT.] College of Oriental Medicine, Kyung-Hee University, Seoul, Republic of Korea, Click here to read

SUO ZhiLi, ZHANG HuiJin, ZHANG ZhiMing, CHEN FuFei, CHEN FuHui: DNA molecular evidences of the hybrids between P. rockii and P. suffruticosa based on ISSR markers. Acta Botanica Yunnanica 2005. 27(1): 42 – 8. (www.wanfangdata.com.cn/qikan/periodical.Articles/ynzwyj/ynzw2005/0501/050105.htm ) [Paeonia rockii is considered to be one of the main progenitors of Chinese tree peony cultivars, and hybridization is likely to be the most important way for incorporation of genetic composition of P. rockii. However, no molecular evidence has shown relatedness of woody peony cultivars to P. rockii so far. In this study, P. rockii was used as a maternal parent crossing with other three Chinese woody peony cultivars (P. suffruticosa ‘Hai Tang Zheng Rong’, P. suffruticosa ‘Yan Zhi Hong’ and P. suffruticosa ‘Sheng Dan Lu’) as paternal parents.The relationships between the F1 hybrids and their parents were analyzed using ISSR (Inter-simple sequence repeat) markers. Our results showed that ISSR fragments present in both parents were detected in the genomes of the F1 generation. Therefore, it is possible that some Chinese woody peony cultivars with a large black-purple blotch at the lower part of petals originated through hybridization with P. rockii as a parent. Our results also suggest that ISSR markers are useful for identification of hybrids and classification of cultivars.]

Wang H, Wei W, Wang NP, Wu CY, Yan SX, Yue L, Zhang LL, Xu SY. Effects of total glucosides of peony on immunological hepatic fibrosis in rats. World J Gastroenterol. 2005 Apr 14;11(14):2124-9. [Abstract: To study the effects of total glucosides of peony (TGP) on immunological hepatic fibrosis induced by human albumin in rats. METHODS: Sixty adult male Sprague-Dawley rats were randomly divided into: Normal group, model group, TGP (60 and 120 mg/kg) treatment groups and colchicines (0.1 mg/kg) treatment group. On the day before the rats were killed, those in TGP or colchicine groups received TGP or colchicine as above from the first day of tail vein injection of human albumin. The rats in normal and model groups were only administered with the same volume of vehicle. At the end of the 16th wk, rats in each group were killed. Blood and tissue specimens were taken. Levels of alanine aminotransferase (ALT), aspartate aminotransferase (AST), nitric oxide (NO), content of malondialdehyde (MDA), activity of superoxide dismutase (SOD) and glutathione peroxidase (GSH-px), were measured by biochemical methods. Serum procollagen type III (PC III) and laminin (LN) were determined by radioimmunoassay. Liver collagen level was determined by measuring hydroxyproline content in fresh liver samples. Hepatic tissue sections were stained with hematoxylin-eosin and examined under a light microscope. RESULTS: Histological results showed that TGP improved the human albumin-induced alterations in the liver structure, alleviated lobular necrosis and significantly lowered collagen content. The antifibrotic effect of TGP was also confirmed by decreased serum content of LN and PCIII in TGP-treated group. Moreover, the treatment with TGP effectively reduced the hydroxyproline content in liver homogenates. However, the level of ALT and AST increased in fibrotic rat but had no significance compared with normal control, whereas the ratio of A/G decreased without significance. TGP had no effect on level of ALT, AST and the ratio of A/G. Furthermore, TGP treatment significantly blocked the increase in MDA and NO, associated with a partial elevation in liver total antioxidant capacity including SOD and GSH-px. CONCLUSION: TGP has beneficial effects on hepatic fibrosis in rats by inhibition of collagen synthesis and decreasing oxidative stress.] Institute of Clinical Pharmacology, Anhui Medical University, Hefei 230032, Anhui Province, China. Click here to read full conplete article.

Wang Jianguo & Zhang Zuoshuang. Herbaceous Peonies of China, ISBN 7 5038 3961 9.

Wang X, Cheng C, Sun Q, Li F, Liu J, Zheng C. Isolation and purification of four flavonoid constituents from the flowers of Paeonia suffruticosa by high-speed counter-current chromatography. J Chromatogr A. 2005 May 20;1075(1-2):127-31. [Abstract: Four flavonoids, apigenin-7-O-neohesperidoside, luteolin-7-O-glucoside, apigenin-7-O-glucoside and kaempferol-7-O-glucoside have been isolated and purified for the first time from the flowers of Paeonia suffruticosa by high-speed counter-current chromatography with a two-phase solvent system composed of ethyl acetate-ethanol-acetic acid-water (4:1:0.25:5, v/v). Then, 5 mg apigenin-7-O-neohesperidoside, 4 mg luteolin-7-O-glucoside, 9 mg apigenin-7-O-glucoside and 2.5 mg kaempferol-7-O-glucoside could be obtained after injecting 40 mg sample and their purities were 94, 97, 97 and 96%, respectively. All these constituents were identified by mass spectrometry and nuclear magnetic resonance.] Test Center, Shandong Academy of Sciences, 19 Keyuan Street, Jinan, Shandong 250014, China.

Zhu, Xiangyun1; Hong, Tao2 (2005): Validation and neotypification of Paeonia rockii subsp. linyanshanii (Paeoniaceae). Taxon, Volume 54, Number 3, August 2005, pp. 806-807(2), Publisher: International Association for Plant Taxonomy [Abstract: "Paeonia rockii subsp. linyanshanii T. Hong & G. L. Osti" was not validly published in 1994 because it was assigned to "Paeonia rockii (S. G. Haw & L. A. Lauener) T. Hong & J. J. Li", which was not then a validly published name. Although the species name was validated in 1998 as Paeonia rockii (S. G. Haw & L. A. Lauener) T. Hong & J. J. Li ex D. Y. Hong, P. rockii subsp. linyanshanii has still not been validly published, although P. suffruticosa var. linyanshanii J. J. Halda was validly published in 1997. P. rockii subsp. linyanshanii is validated here, based on Handa's varietal name, and, because the holotype was not preserved, a neo-type is designated. Keywords: PAEONIACEAE; PAEONIA ROCKII SUBSP. LINYANSHANII; VALIDATION Affiliations: 1: Institute of Botany, the Chinese Academy of Sciences, Beijing 100093, China 2: Chinese Academy of Forestry, Beijing 100091, China] online available under the following (link)

[Gmelin-Ausstellung in Tübingen]

Carsten Burkhardt's Web Project Paeonia - The Peony Library

Paeonia-Literatur 2005